How beneficial are COVID-19 vaccines in immunocompromised people

Pfizer  COVID-19 vaccines in news Photos

Pfizer COVID-19 vaccines in news Photos

After a long battle with COVID-19, the administration of the vaccine has certainly brought a sigh of relief. A double dose of the coronavirus vaccine can limit the risk of infection and prevent the virus from causing a serious infection that can be hospitalised or fatal. However, in people with compromised immunity, there is uncertainty about the vaccine's effectiveness and the level of protection it would provide


People with weakened immunity have an underlying disease that weakens their immunity and puts them at serious risk of infection. Simply put, these people's immune systems are not strong enough to fight off the virus and prevent it from causing serious health problems. This category includes people with cancer, organ transplants, metabolic and autoimmune diseases, and people taking drugs that alter their immune response. This leaves most people wondering if the vaccine could work for them. 


Most vaccines currently in use contain viral material. When these substances enter our bodies, cells instruct our immune cells to make a harmless protein according to the structure of the virus. Once our cells make copies of the protein, the body destroys the genetic material in the vaccine. Our body stores the protein structure in its memory cells to fight the virus that will cause COVID-19 in a future infection. The immune system doesn't work as well in people who are immunocompromised. It is believed that the immune system may not be able to produce a sufficient response to the vaccine. The question arises whether the vaccine can actually reduce the risk of infection.


A specific study on organ transplant recipients suggests they have a poor antibody response to COVID-19 vaccines. In addition, only 17% of all people in the study developed a detectable antibody response approximately 2 weeks after the first dose of an mRNA vaccine. After the second dose, antibody responses were detectable in 54 percent of participants. Researchers in the study also found that transplant patients were at serious risk of infection and serious consequences.However, it's important to remember that the study was conducted specifically in organ transplant recipients. The antibody response produced by vaccines in people with other immunocompromised diseases can vary.

Experts in medical sciences believe that strengthening immunocompromised people can reduce the risk of infection and hospitalisation. The third dose can increase the immune response and the level of antibody response to COVID-19. Given the effectiveness of the third dose, it would be easier to indicate the need for the fourth and fifth doses. Until then, taking all COVID-related precautions is the only way to protect yourself. When you go out, wear a mouth cap, stand 1.5 meters away, practice good hygiene habits and get vaccinated.


Sources:- India today
 

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