CSIR-Laxai to start with the clinical preliminaries on Niclosamide for Covid

in image medicine for clinical study illustration

in image medicine for clinical study illustration

A phase II clinical study of Niclosamide, the anthelmintic medicine for the therapy of covid-19, was begun by the CSIR, Council of Scientific and Industrial Research in conjunction with Laxai Life Sciences Pvt Ltd. The research is an open-label, randomized, multi-center Phase II clinical investigation aimed at assessing the effectiveness, safety, and tolerance of Niclosamide in treating Covid-19 patients hospitalized.

Previously, Niclosamide was widely used in teens and adults for treatments for tapeworm infection. The drug's safety profile was examined over time and was proven to be safe for human consumption at various dose levels, the authorities stated. 

"The subject expert committee (SEC) has given its recommendations to conduct this Phase II clinical trial using Niclosamide, which is a generic, affordable drug and easily available in India and therefore can be made available to our population," said Dr. Shekhar C Mande, Director General, CSIR.

Independently, Bengaluru has recently proven that Niclosamide is also a possible SARS-CoV2 inhibitor for entry inhibiting viral invasion via an ionic strength endocytic route, in cooperation with CSIR-IIIM, Jammu, and NCBS. Given the two independent experimental trials, the potential therapeutic candidate in Covid-19 patients currently contains Niclosamide.

"The Active Pharmaceutical Ingredient (API) is being made by Laxai Life Sciences based on improved technology developed at IICT, and the lab is a partner in this important clinical trial, which could provide cost-effective therapeutic options for patients if the trial is successful," Dr. Srivari Chandrashekhar, Director CSIR-II CT Hyderabad said in an official note. 

Source-mint

More

SPORTS

IPL 2021 Final

IPL 2021 Finals, to be played between CSK and KKR, know the venue, predicted XI, and weather

The 2021 IPL Finals will see MS Dhoni’s Chennai Super Kings and Eoin Morgan Kolkata Knight Riders in the power-packed, high octane grand finale...

T20 World Cup

Indians to face Australians in warm up matches of the T20 World Cup

India is going to take along England and Australia during the two warm up games, and will be further gearing up for the upcoming T20 World Cup matches...

States & UTs

Delhi Government

NCPCR Sends Notice to Delhi Government

The National Commission for Protection of Child Rights (NCPCR|) has pulled up the Delhi authorities over a promotional video. A criticism on this rega...

Singhu protest

At Singhu protest site, dead man with wrist cut off found tied to barricade

The frame of an unidentified guy with one in every of his wrists chopped off turned into discovered close to the farmers’ protest web website on...

POLITICS

PM Modi

The center's 7 new defense companies will become one giant military base: PM Modi

Prime Minister Narendra Modi on Thursday launched seven new companies that will enter the defense se...

Akhilesh Yadav (Samjwadi Vijay Yatra)

Akhilesh Yadav Sounds Like A Bugle For Polls In Uttar Pradesh, Launches "Samjwadi Vijay Yatra" Across The Country

Samajwadi Party spokesman Rajendra Chaudhary said that after exiting Ganga Bridge, the yatra will ta...

ENTERTAINMENT

Sardar Udham Movie (Pic Credit: Amazon Prime Video)

Vicky Kaushal Film is recreates Horrors of Jallianwala Bagh Massacre.(Sardar Udham Movie Review)

Sardar Udham is an exclusive recreation altogether from the movies Shoojt Sircar has directed so far...

Aryan Khan,Gauri Khan & SRK

Aryan Khan had video call with Gauri Khan & SRK and received money order of Rs4500

Aryan Khan received a money  order for Rs 4,500 to order food and other items from the Arthur R...

About

The Live Newz is an independent, budding and online news portal that came into existence recently. Our mission is to create and deliver the finest news for the readers. We act as a cutting-edge platform that provides the users with every update on recent happenings. We aspire to be true to the journalistic values and maintain the standard of its excellence by presenting the truth to the readers.